Retinal Biologics Market

Global Retinal Biologics Market Size, Share & Industry Trends Analysis Report By Indication (Macular Degeneration, Diabetic Retinopathy), By Drug Class (VEGF-A Antagonist and Others), By Distribution Channel, By Regional Outlook and Forecast, 2023 - 2030

Report Id: KBV-16636 Publication Date: July-2023 Number of Pages: 229
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Market Report Description

The Global Retinal Biologics Market size is expected to reach $20.7 billion by 2030, rising at a market growth of 5.4% CAGR during the forecast period.

As people age, a variety of diseases and issues can arise. The senior population is more at risk of the age-related progression of AMD disease thus, the macular degeneration segment will register around 60% share in the market by 2030. For example, By 2050, there will be about 1.5 billion people on the planet, a rise of more than three times the current population. Additionally, it is anticipated that by this time, 16.0% of people will be over the age of 60 worldwide. One out of every six people will be 65 or older by the middle of the twenty-first century. The global increase in the number and prevalence of older people is known as the "population aging phenomenon." In 2019, there were 703 million people worldwide who were 65 or older. People 65 and over made up 9% more of the population in 2019 than they did in 2018. Some of the factors impacting the market Technological advances aiding in the development of retinal biologics, Rising prevalence of retinal and eye issues, and longer time periods for drug approval.

Retinal Biologics Market Size - Global Opportunities and Trends Analysis Report 2019-2030

Retinal biologic products have undergone technological breakthroughs that have improved their safety and effectiveness profiles, which has led to a rise in patient uptake across the globe. Significant R&D expenditures and business partnerships among market players are advantageous for developing retinal biology. The technical advances place a strong focus on research and development (R&D) pertaining to retinal gene treatments conducted by various institutes, biologics firms, and innovative product launches by key players in the form of implants and biologics. Additionally, Because of the increasing number of initiatives taken by various healthcare organizations, governmental entities, and industry actors, there is a greater awareness among the general public about ocular problems, which is leading to a higher diagnostic and treatment rate in the population. Concern regarding diabetic retinopathy has grown as more adults with type I and type II diabetes are losing their vision as a result of the disease. Thus, technological improvements in retinal biologics products and increasing prevalence of ocular issues will augment the expansion of the market in the coming years.

However, a number of pricey regulatory approvals and research phases are necessary for drug approval. The process of approving a medicine involves several phases of regulatory agency screening, including about four clinical trial steps. The costs of failing studies are high because clinical trial phases need large investments. For instance, according to a Forbes article, a medication producer invests approximately $350 million in each therapy before it is put on the market. Long wait times also cost these producers money, which hinders the expansion of the market. Furthermore, workflows in the healthcare industry were affected globally by the COVID-19 pandemic. Several areas of the healthcare sector, as well as several other industries, temporarily closed their doors due to the sickness. The COVID-19-led worldwide economic slowdown caused a drop in the market for retinal biologics in 2020. The pandemic also caused supply chains in several end-user industries to fall, including the pharmaceutical, healthcare, and industrial sectors. This limited the market and impacted the release of innovative medicines.

Drug Class Outlook

On the basis of drug class, the market is segmented into VEGF-A antagonist and others. The others segment recorded a significant revenue share in the market in 2022. The other segment mostly includes biologics developed from TNF-α. The pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-α) is generated by macrophages and T-cells. It is significant in both inflammation and apoptosis. TNF-α is considered part of developing inflammatory, edematous, neovascular, and neurodegenerative illnesses in the eye.

Retinal Biologics Market Share and Industry Analysis Report 2022

Distribution Channel Outlook

Based on distribution channel, the market is divided into hospital pharmacy, online pharmacy, and retail pharmacy. The online pharmacy segment procured a considerable growth rate in the market in 2022. One of the key factors influencing the segment's growth is the increasing number of patients visiting ophthalmology clinics for the treatment of various eye conditions. In both established and developing nations, there are more and more people using the internet, and patients are increasingly choosing to buy their drugs online.

Indication Outlook

Based on indication, the market is categorized into macular degeneration, diabetic retinopathy, and others. The macular degeneration segment procured the highest revenue share in the market in 2022. Retinal biologics can help maintain eyesight and stop additional vision loss in people with macular degeneration by lowering inflammation in the retina and limiting the formation of aberrant blood vessels. Biologics used early and effectively can sometimes stabilize or even improve vision. The frequency of injections or treatments is decreased by some retinal biologics' extended-release formulations.

Retinal Biologics Market Report Coverage
Report AttributeDetails
Market size value in 2022USD 13.7 Billion
Market size forecast in 2030USD 20.7 Billion
Base Year2022
Historical Period2019 to 2021
Forecast Period2023 to 2030
Revenue Growth RateCAGR of 5.4% from 2023 to 2030
Number of Pages229
Number of Table340
Report coverageMarket Trends, Revenue Estimation and Forecast, Segmentation Analysis, Regional and Country Breakdown, Companies Strategic Developments, Company Profiling
Segments coveredIndication, Drug Class, Distribution Channel, Region
Country scopeUS, Canada, Mexico, Germany, UK, France, Russia, Spain, Italy, China, Japan, India, South Korea, Singapore, Malaysia, Brazil, Argentina, UAE, Saudi Arabia, South Africa, Nigeria
Growth Drivers
  • Technological advances aiding in the development of retinal biologics
  • Rising prevalence of retinal and eye issues
  • Longer time periods for drug approval

Regional Outlook

Region-wise, the market is analyzed across North America, Europe, Asia Pacific, and LAMEA. The North America region recorded the largest revenue share in the market in 2022. The existence of numerous significant players, including Bayer AG, and Novartis AG, as well as developments in the production of retinal biologics, are driving the market's expansion. Additionally, easier access to retinal biologics medications and greater public awareness of the importance of early detection and treatment are key factors driving market expansion in this region. In addition, a strong network of hospitals, clinics, and research institutions makes up the healthcare infrastructure. This infrastructure aids in the creation, use, and study of retinal biology.

Free Valuable Insights: Global Retinal Biologics Market size to reach USD 20.7 Billion by 2030

The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Novartis AG, Amgen, Inc., AbbVie, Inc., Bayer AG, Regeneron Pharmaceuticals, Inc., Santen Pharmaceutical Co., Ltd., Bausch Health Companies, Inc., F. Hoffmann-La Roche Ltd., MeiraGTx Holdings plc and Oxurion NV.

Strategies deployed in the Market

  • Jul-2023: Bausch + Lomb acquired the Blink over-the-counter (OTC) line of eye drops from Johnson & Johnson Vision. The acquisition expanded the former company's portfolio of OTC eye care products and the addition would enable the company to provide enhanced convenience to consumers.
  • May-2023: Bausch + Lomb, the eyecare division of Bausch Health, received approval from the U.S. Food and Drug Administration for Miebo drops for dry eye disease. The medication fills a sizable gap in patient care as it is the only FDA-approved treatment to specifically target tear evaporation.
  • Feb-2023: AbbVie extended its collaboration with Capsida Biotherapeutics, a fully integrated next-generation gene therapy platform company, for developing genetic medicines for eye problems. Capsida's cutting-edge adeno-associated virus (AAV) engineering platform and manufacturing expertise will be integrated with AbbVie's comprehensive capabilities to identify and advance three candidates.
  • Aug-2022: Bausch + Lomb partnered with Munich Surgical Planning (MSI), a subsidiary of Heidelberg Engineering. To meet the rising demand for digital microscopy, this partnership aimed to bring together Bausch + Lomb's surgical expertise in the cataract, refractive, and vitreoretinal space with MSI's visualization and image guidance expertise, including an integrated high-speed SSOCT powered by Heidelberg Engineering.
  • Jul-2022: Roche came into partnership with Avista Therapeutics, a company focused on developing innovative gene therapies for retinal diseases, for developing novel AAV gene therapy vectors for eyes. The partnership aimed to use Avista's single-cell adeno-associated virus engineering (scAAVengr) platform technology to create intravitreal AAV capsids that fit a capsid profile specified by Roche. Moreover, Roche is in charge of conducting preclinical, clinical, and commercialization activities for gene therapy programs using these novel capsids, which is different from Avista's internal pipeline. Roche will also have the right to evaluate and license novel capsids from Avista.
  • Feb-2022: Roche received the U.S. Food and Drug Administration approval for Vabysmo (faricimab-svoa) for the treatment of neovascular Diabetic Macular Edema (DME) and Age-related Macular Degeneration (nAMD). Vabysmo neutralizes the disease-related proteins angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A), which are associated with a range of retinal disorders that can impair vision.
  • Jan-2022: AbbVie got the U.S. Food and Drug Administration (FDA) approval for RINVOQ® (upadacitinib). This medication is indicated for the treatment of moderate to severe atopic dermatitis in children 12 years of age and above and adults.
  • Dec-2021: Novartis signed an agreement to acquire Gyroscope Therapeutics, a clinical-stage gene therapy company. Through this acquisition, Novartis would achieve access to the prior guide experimental gene treatment, GT005.
  • Mar-2021: Roche signed a collaboration and licensing agreement with SemaThera, a company focused on creating novel therapies for retinopathies. The partnership was focused on creating SemaThera's exciting new class of biologicals for the management of ischemic retinal disorders, such as diabetic retinopathy.

Scope of the Study

Market Segments Covered in the Report:

By Indication

  • Macular Degeneration
  • Diabetic Retinopathy
  • Others

By Drug Class

  • VEGF-A Antagonist
  • Others

By Distribution Channel

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy

By Geography

  • North America
    • US
    • Canada
    • Mexico
    • Rest of North America
  • Europe
    • Germany
    • UK
    • France
    • Russia
    • Spain
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Singapore
    • Malaysia
    • Rest of Asia Pacific
    • Brazil
    • Argentina
    • UAE
    • Saudi Arabia
    • South Africa
    • Nigeria
    • Rest of LAMEA

Key Market Players

List of Companies Profiled in the Report:

  • Novartis AG
  • Amgen, Inc.
  • AbbVie, Inc.
  • Bayer AG
  • Regeneron Pharmaceuticals, Inc.
  • Santen Pharmaceutical Co., Ltd.
  • Bausch Health Companies, Inc.
  • F.Hoffmann-La Roche Ltd.
  • MeiraGTx Holdings plc
  • Oxurion NV
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Frequently Asked Questions About This Report

The Market size is projected to reach USD 20.7 billion by 2030.

Technological advances aiding in the development of retinal biologics are driving the Market in coming years, however, Longer time periods for drug approval restraints the growth of the Market.

Novartis AG, Amgen, Inc., AbbVie, Inc., Bayer AG, Regeneron Pharmaceuticals, Inc., Santen Pharmaceutical Co., Ltd., Bausch Health Companies, Inc., F. Hoffmann-La Roche Ltd., MeiraGTx Holdings plc and Oxurion NV.

The VEGF-A Antagonist is leading the Market by Drug Class in 2022; thereby, achieving a market value of $16.1 billion by 2030.

The North America region dominated the Market by Region in 2022 and would continue to be a dominant market till 2030; thereby, achieving a market value of $10.9 billion by 2030.



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