Botulinum Toxin Market Size, Trends Analysis & Forecast, 2028

Global Botulinum Toxin Market Size, Share & Industry Trends Analysis Report By Product, By Application (Therapeutic and Aesthetic), By End User (Hospitals, Dermatology Clinics and Spas & Cosmetic Centers, By Regional Outlook and Forecast, 2022 - 2028

Published Date: August-2022 | Number of Pages: 162 | Format: PDF | Report ID: KBV-10713

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Get in-depth analysis of the COVID-19 impact on the Botulinum Toxin Market

Market Report Description

The Global Botulinum Toxin Market size is expected to reach $10.5 billion by 2028, rising at a market growth of 10.8% CAGR during the forecast period.

Botulinum toxin is a neurotoxin, which is one of the most lethal biological chemicals created by the bacterium Clostridium botulinum. Eight exotoxins with distinct antigens are produced by botulinum C. The main neurotransmitter at the neuromuscular junction, acetylcholine, is blocked by all serotypes, interfering with neuronal transmission and paralyzing muscles. Botulinum toxin A injection-induced weakness often lasts for three months.

Botulinum Toxin Market - Global Opportunities and Trends Analysis Report 2018-2028

Strabismus, focal dystonia, hemifacial spasm, various spastic movement disorders, hyperhidrosis, headaches, hypersalivation, and some chronic conditions that only partially respond to medical treatment are just a few of the many medical conditions that can now be controlled with the help of botulinum toxins. The number of potential new symptoms is growing quickly. Cosmetologically applications as well as dermatological ones, like hyperhidrosis to correcting lines, creases, and wrinkles all over the face, neck, chin, and chest are benefitted with this compound.

Botulinum toxin injections are often well tolerated and have very few adverse effects. To effectively use botulinum toxins in clinical practice, one must possess a thorough understanding and expertise of the functional anatomy of the mimetic muscles. Botulinum toxin, one of the most toxic biological molecules, is also known as miracle poison. This neurotoxin is produced by the anaerobic, gram-positive rod-shaped bacterium Clostridium botulinum, which is typically found on plants, in soil, water, and animal intestinal tracts.

Botulinum toxin type A can effectively treat strabismus in humans. Botulinum toxin was subsequently authorized for the treatment of several spasticity problems as well as a variety of other ailments. It is currently utilized in practically all medical subspecialties. The FDA authorized the cosmetic use of Botox (Botulinum toxin-A) in 2002 to temporarily lessen glabellar forehead frown lines.

COVID-19 Impact Analysis

The demand-supply equilibrium across the whole healthcare sector was severely disrupted by the pandemic. The botulinum toxin market has been considerably impacted due to this abrupt burden on the worldwide healthcare infrastructure. Many cosmetic treatments and operations were initially put on hold as a result of domestic as well as international lockdowns that were imposed in the majority of countries. However, due to the higher demand during the pandemic, sales of botulinum toxins, like Botox, witnessed a spike. Many dermatologists and plastic surgeons attribute the growth to people with the desire to look their best for conferences and online meetings, as well as having more time to attend consultations and recover from treatments.

Market Growth Factors

High Levels Of Effectiveness And Efficiency In Therapeutic And Cosmetic Applications

Botulinum toxin is considered to be primarily utilized to treat cosmetic diseases, however, its medicinal uses go far beyond this. Botulinum toxin is a successful alternative to conventional therapy for patients with chronic migraine, muscle spasms, reagent bladder, and hyperhidrosis. Additionally, it has been found that botulinum toxin is quite effective at reducing chronic pelvic discomfort in females with endometriosis. People who have undergone botulinum toxin therapy are able to maintain their mobility for as long as 11 months.

Increasing Demand For Minimal Invasion

botulinum toxin is utilized to treat a variety of aging-related problems, including crow's feet, glabellar lines, forehead lines, and others. People over 40 are therefore more likely to experience these indicators of aging. Therefore, botulinum toxin operations are becoming increasingly popular among people between the ages of 40 and 54. Among the most common non-invasive rejuvenation techniques, injectable botulinum toxin, soft-tissue fillers, as well as chemical peels each have particular uses for enhancing facial appearances.

Market Restraining Factors

Side Effects Related To The Use Of This Substance

Although botulinum toxin is typically regarded as safe when used in a clinical environment, it has the potential to have major negative effects. Botulinum toxin can most frequently be injected into the incorrect muscle group or over time can travel from the injection site, temporarily paralyzing undesired muscles. Unintentional paralysis of face muscles is the main cause of the side effects of cosmetic use. These include difficulty eating, muscle weakness, and partial facial paralysis.

Product Outlook

On the basis of Product, the Botulinum Toxin Market is bifurcated into Type A and Type B. In 2021, the Type-A segment witnessed the biggest revenue share of the botulinum toxin market. The increase in the growth of the market is attributed to the rise in the number of cases of sialorrhea all over the world. There are a number of commercially available botulinum toxin type-A medications, including Botox and Dysport, that have undergone clinical testing and have been shown to be both safe and effective over the long term with the fewest side effects.

Botulinum Toxin Market Share and Industry Analysis Report 2021

Application Outlook

Based on Application, the Botulinum Toxin Market is divided into Therapeutic and Aesthetic. In 2021, the aesthetics segment recorded a significant revenue share of the botulinum toxin market. Botulinum toxin is a staple of the cosmetology toolbox. There have been more cosmetic procedures performed as a result of increased aesthetic consciousness and technology breakthroughs in both developed and developing nations.

End-User Outlook

By End-User, the Botulinum Toxin Market is segregated into Hospitals, Dermatology Clinics, and Spas & Cosmetic Centers. In 2021, the spas and cosmetic centers segment recorded a substantial revenue share of the botulinum toxin market. The segment's growth is primarily attributed to a higher inclination for aesthetic operations in dermatological clinics, spas, and cosmetic centers.

Botulinum Toxin Market Report Coverage
Report Attribute Details
Market size value in 2021 USD 5.2 Billion
Market size forecast in 2028 USD 10.5 Billion
Base Year 2021
Historical Period 2018 to 2020
Forecast Period 2022 to 2028
Revenue Growth Rate CAGR of 10.8% from 2022 to 2028
Number of Pages 162
Number of Tables 327
Report coverage Market Trends, Revenue Estimation and Forecast, Segmentation Analysis, Regional and Country Breakdown, Companies Strategic Developments, Company Profiling
Segments covered Product, Application, End User, Region
Country scope US, Canada, Mexico, Germany, UK, France, Russia, Spain, Italy, China, Japan, India, South Korea, Singapore, Malaysia, Brazil, Argentina, UAE, Saudi Arabia, South Africa, Nigeria
Growth Drivers
  • High Levels Of Effectiveness And Efficiency In Therapeutic And Cosmetic Applications
  • Increasing Demand For Minimal Invasion
  • Side Effects Related To The Use Of This Substance

Regional Outlook

Region-Wise, the Botulinum Toxin Market is analyzed across North America, Europe, Asia-Pacific, and LAMEA. In 2021, North America dominated the botulinum toxin market with the largest revenue share. The growth of regional market is expanding due to rising disposable income as well as an increase in cosmetic operations. Moreover, there is a significant number of market players operating in the region, who are increasing their focus and efforts in order to fulfill the rising demands of customers.

Free Valuable Insights: Global Botulinum Toxin Market size to reach USD 10.5 Billion by 2028

The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Evolus, Inc. (Alphaeon Corporation), Merz Pharma GmbH & Co. KGaA, AbbVie, Inc., Ipsen Pharma, Galderma S.A., USWM, LLC, and Metabiologics, Inc. (Object Pharma).

Strategies deployed in Botulinum Toxin Market

  • Jul-2021: Allergan plc, subsidiary of AbbVie, Inc. received the US FDA approval for its label expansion of BOTOX to include muscles in order to treat upper limb spasticity among adults. This acquisition aimed to complement the company's excellence in neurotoxin science and highlight the benefits of BOTOX in the treatment of upper limb spasticity.
  • Nov-2020: Galderma expanded its geographical footprint in China with the launch of its Dysport. With this launch, the company aimed to highlight its commitment to introducing new innovations in the aesthetic market in order to grow while also fulfilling the demand of its customers across China.
  • May-2020: AbbVie acquired Allergan, an American global pharmaceutical company. Under this acquisition, the company aimed to leverage growth prospects in neuroscience through the addition of Allergan's Botox therapeutics, Vraylar, and Ubrelvy.
  • Oct-2019: Allergan plc, subsidiary of AbbVie, Inc. received the US FDA approval for its supplemental biologics license application for BOTOX to treat pediatric patients from age 2 years-17 years. This acquisition aimed to reinforce the approval of the 11th BOTOX therapeutic indication in the same year.
  • Sep-2019: Ipsen received approval for expanded use of its Dysport for injection to provide treatment for upper limb spasticity among children of age 2 or older. Through this approval, the company aimed to complement its neurotoxin research legacy as well as its strategy to bring advancements in patient care.
  • May-2019: Merz received European approval for the Xeomin, a symptomatic treatment option for chronic sialorrhea in adult patients. The new treatment aimed to aid patients in enhancing the quality of life of patients with sialorrhea.
  • Feb-2019: Evolus received the US FDA approval for its Jeuveau. With the new Hi-Pure technology-built neurotoxin, the company aimed to offer enhanced aesthetics
  • Jan-2018: Ipsen received approval for its DYSPORT THERAPEUTIC from Health Canada for the treatment of limb spasticity among pediatric patients in patients of age 2 or older. With this acquisition, the company aimed to offer a treatment that provides improved movement and stiffness.

Scope of the Study

Market Segments Covered in the Report:

By Product

  • Type A
  • Type B

By Application

  • Therapeutic
  • Aesthetic

By End User

  • Hospitals
  • Dermatology Clinics
  • Spas & Cosmetic Centers

By Geography

  • North America
    • US
    • Canada
    • Mexico
    • Rest of North America
  • Europe
    • Germany
    • UK
    • France
    • Russia
    • Spain
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Singapore
    • Malaysia
    • Rest of Asia Pacific
    • Brazil
    • Argentina
    • UAE
    • Saudi Arabia
    • South Africa
    • Nigeria
    • Rest of LAMEA

Key Market Players

List of Companies Profiled in the Report:

  • Evolus, Inc. (Alphaeon Corporation)
  • Merz Pharma GmbH & Co. KGaA
  • AbbVie, Inc.
  • Ipsen Pharma
  • Galderma S.A.
  • Metabiologics, Inc. (Object Pharma)

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Related Reports:

North America Botulinum Toxin Market Report 2022-2028

Europe Botulinum Toxin Market Report 2022-2028

Asia Pacific Botulinum Toxin Market Report 2022-2028

LAMEA Botulinum Toxin Market Report 2022-2028


The Botulinum Toxin Market size is projected to reach USD 10.5 billion by 2028.

High Levels Of Effectiveness And Efficiency In Therapeutic And Cosmetic Applications are driving the market in coming years, however, Side Effects Related To The Use Of This Substance restraints the growth of the market.

Evolus, Inc. (Alphaeon Corporation), Merz Pharma GmbH & Co. KGaA, AbbVie, Inc., Ipsen Pharma, Galderma S.A., USWM, LLC, and Metabiologics, Inc. (Object Pharma).

The expected CAGR of the Botulinum Toxin Market is 10.8% from 2022 to 2028.

The Therapeutic segment acquired maximum revenue share in the Global Botulinum Toxin Market by Application in 2021 thereby, achieving a market value of $5.9 billion by 2028.

The North America market dominated the Global Botulinum Toxin Market by Region in 2021, and would continue to be a dominant market till 2028; thereby, achieving a market value of $3.8 billion by 2028.

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